Reto Brun Selected Research

furamidine (DB75)

7/2005	Efficacy of DB289 in Thai patients with Plasmodium vivax or acute, uncomplicated Plasmodium falciparum infections.
8/2004	O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of Trypanosoma brucei rhodesiense infection.
2/2004	Characterization of a novel DNA minor-groove complex.

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Reto Brun Research Topics

Disease

48	Malaria 10/2021 - 08/2002
36	African Trypanosomiasis (Nagana) 01/2018 - 08/2002
15	Infections 10/2016 - 01/2002
9	Chagas Disease (American Trypanosomiasis) 01/2012 - 08/2002
8	Trypanosomiasis 01/2022 - 02/2004
7	Neglected Diseases 09/2015 - 04/2008
7	Body Weight (Weight, Body) 11/2013 - 06/2003
6	Neoplasms (Cancer) 11/2019 - 06/2003
6	Leishmaniasis 01/2012 - 08/2002
5	Parasitic Diseases (Parasitic Disease) 01/2018 - 12/2004
4	Leukemia 01/2018 - 12/2016
3	Pancreatic Neoplasms (Pancreatic Cancer) 11/2018 - 10/2017
3	Communicable Diseases (Infectious Diseases) 08/2015 - 02/2004
2	Multiple Myeloma 11/2019 - 01/2017
2	Central Nervous System Infections (Central Nervous System Infection) 08/2014 - 07/2014
2	Parasitemia 11/2013 - 03/2013
2	Visceral Leishmaniasis (Kala Azar) 03/2013 - 01/2010
2	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2013 - 07/2006
2	Tuberculosis (Tuberculoses) 02/2010 - 11/2009
1	Fibrosarcoma 11/2019
1	Carcinoma (Carcinomatosis) 11/2019
1	Chronic Disease (Chronic Diseases) 12/2011

Drug/Important Bio-Agent (IBA)

31	Pharmaceutical PreparationsIBA 01/2018 - 08/2003
11	Pentamidine (NebuPent)FDA LinkGeneric 01/2018 - 07/2005
10	Biological ProductsIBA 09/2015 - 08/2002
9	Antimalarials (Antimalarial Agents)IBA 08/2015 - 08/2004
7	AlkaloidsIBA 11/2018 - 05/2004
6	Chloroquine (Aralen)FDA LinkGeneric 04/2015 - 11/2002
5	artemisinin (artemisinine)IBA 08/2015 - 08/2004
5	EnzymesIBA 08/2015 - 10/2003
4	ProdrugsIBA 02/2015 - 08/2004
3	DNA (Deoxyribonucleic Acid)IBA 11/2015 - 02/2004
3	Fatty Acids (Saturated Fatty Acids)IBA 08/2015 - 11/2010
3	Eflornithine (Ornidyl)FDA Link 02/2014 - 06/2003
3	fexinidazoleIBA 12/2011 - 12/2010
3	Anti-Bacterial Agents (Antibiotics)IBA 05/2011 - 02/2004
3	Melarsoprol (Mel B)IBA 11/2008 - 10/2003
3	ArtesunateIBA 02/2008 - 08/2004
3	furamidine (DB75)IBA 07/2005 - 02/2004
2	Antiparasitic Agents (Antiparasitics)IBA 10/2021 - 02/2014
2	jozimine A2IBA 11/2019 - 10/2017
2	diminazene aceturateIBA 01/2017 - 02/2004
2	SolventsIBA 08/2015 - 05/2010
2	Pyrimethamine (Daraprim)FDA Link 04/2015 - 06/2010
2	NifurtimoxIBA 02/2014 - 01/2012
2	cynaropicrinIBA 11/2013 - 11/2013
2	4-nitroimidazoleIBA 12/2011 - 12/2010
2	dUTP pyrophosphataseIBA 10/2011 - 02/2011
2	DeoxyuridineIBA 10/2011 - 02/2005
2	DiminazeneIBA 07/2011 - 12/2009
2	Phosphogluconate Dehydrogenase (Dehydrogenase, Phosphogluconate)IBA 08/2007 - 07/2003
2	Artemether FDA Link 02/2006 - 08/2004
2	thiolactomycinIBA 09/2005 - 02/2004
2	Antimicrobial PeptidesIBA 12/2004 - 12/2002
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2022
1	E 10 (E-10)IBA 01/2018
1	Fluorouracil (Carac)FDA LinkGeneric 01/2018
1	indoleIBA 01/2018
1	rhodesainIBA 01/2018
1	AN11736IBA 01/2018
1	TriazolesIBA 01/2018
1	AmidesIBA 01/2018
1	Ether (Diethyl Ether)IBA 01/2018
1	benzimidazoleIBA 01/2018
1	Cysteine Proteases (Cysteine Protease)IBA 01/2018
1	ancistrobenomine BIBA 09/2017
1	SteroidsIBA 07/2017
1	dioncophylline AIBA 01/2017
1	isometamidium chloride (ISMM)IBA 01/2017
1	homidium chlorideIBA 01/2017
1	P 11 (P-11)IBA 01/2017
1	Melphalan (Alkeran)FDA LinkGeneric 01/2017
1	ancistectorine DIBA 12/2016
1	ACT-451840IBA 10/2016
1	NucleotidesIBA 01/2016
1	Alkylating AgentsIBA 11/2015
1	Proteins (Proteins, Gene)FDA Link 09/2015
1	Antiprotozoal AgentsIBA 08/2015
1	Volatile Oils (Essential Oils)IBA 08/2015
1	CPD0905IBA 08/2014
1	apicidinIBA 11/2013
1	ChloridesIBA 03/2013
1	N- methoxy- 6- (5- (4- (N- methoxyamidino)phenyl)furan- 2- yl)nicotinamidineIBA 01/2012
1	ElementsIBA 01/2012
1	pafuramidineIBA 01/2012
1	Agrochemicals (Agricultural Chemicals)IBA 01/2012
1	AminesIBA 12/2011
1	isoindigotinIBA 11/2011
1	Thioredoxin-Disulfide ReductaseIBA 10/2011
1	Plant ExtractsIBA 10/2011
1	AntioxidantsIBA 10/2011
1	LigandsIBA 10/2011
1	furanIBA 07/2011
1	diphenyl (biphenyl)IBA 07/2011
1	NitroimidazolesIBA 06/2011
1	SCYX 7158IBA 06/2011

Therapy/Procedure

5	Therapeutics 02/2014 - 06/2003
3	Traditional Medicine (Folk Remedies) 05/2014 - 03/2010
2	Drug Therapy (Chemotherapy) 02/2015 - 08/2004
2	Oral Administration 12/2010 - 02/2008